Penile paraffinoma: a case report.

Area of Science:

• Urology
• Dermatopathology
• Plastic Surgery

Background:

• Penile paraffinoma, also known as sclerosing lipogranuloma, results from voluntary injection of liquid paraffin for cosmetic penis enlargement.
• This non-biodegradable synthetic lipid triggers a chronic fibroproductive inflammatory response in subcutaneous tissue.
• The procedure is often performed by untrained individuals, leading to significant health risks.

Observation:

• A case of recurrent penile paraffinoma is presented, involving chronic inflammation and xantogranulomatous changes.
• Histological examination revealed lipid droplets in dermal and subcutaneous tissues, confirmed by oil red and Sudan staining.
• The patient required extensive surgical intervention, including subcutaneous tissue excision and skin grafting.

Findings:

• Human tissues lack enzymes to metabolize synthetic lipids like paraffin, leading to persistent foreign body reactions.
• Complications include genital mutilation, sexual dysfunction, and the tendency for paraffinomas to recur post-surgery.
• Differential diagnosis and treatment options for penile paraffinoma are discussed, highlighting the limitations of current surgical approaches.

Implications:

• Recurrent penile paraffinoma poses significant challenges in management, often requiring complex reconstructive surgery.
• Understanding the histopathology and inflammatory response is crucial for accurate diagnosis and treatment planning.
• This case underscores the dangers of non-medical cosmetic procedures and the need for patient education regarding potential complications.