Related Experiment Video
Updated: Sep 27, 2025

In vitro Assessment of Myocardial Protection following Hypothermia-Preconditioning in a Human Cardiac Myocytes Model
Published on: October 27, 2020
Clinically induced hypothermia with cardiopulmonary support in a high-risk patient undergoing carotid endarterectomy
Kjersti Hervik1, Torvind Olav Næsheim2, Truls Myrmel1
1Department of Cardiothoracic and Vascular Surgery, University Hospital of North Norway, Tromsø, Norway.
Insights
Clinically induced hypothermia controlled by cardiopulmonary bypass protected a high-risk patient from stroke during carotid surgery. This hypothermia strategy mitigated stroke risk from hypoperfusion caused by contralateral carotid occlusion.
Area of Science:
- Neurosurgery
- Cardiovascular Surgery
- Neurology
Background:
- Contralateral carotid artery occlusion poses a significant stroke risk during carotid endarterectomy due to potential hypoperfusion.
- High-risk surgical candidates require specialized protective strategies to minimize perioperative neurological complications.
Observation:
- A patient with crescendo cerebral ischemic events presented for carotid endarterectomy with contralateral carotid occlusion.
- This patient was deemed high-risk for stroke due to the underlying condition and surgical necessity.
Findings:
- Clinically induced hypothermia, managed with cardiopulmonary bypass, was successfully employed as a neuroprotective measure.
- The hypothermia protocol effectively prevented stroke in this high-risk patient during the surgical procedure.
Implications:
- Induced hypothermia via cardiopulmonary bypass may be a viable protective strategy for high-risk patients undergoing carotid surgery.
- This case highlights a potential method to reduce stroke incidence in challenging surgical scenarios involving carotid artery disease.
Abstract:
Contralateral carotid occlusion increases the risk of stroke by hypoperfusion in patients undergoing carotid surgery. We present the case of a high-risk patient with crescendo cerebral ischemic events, for whom clinically induced hypothermia controlled by cardiopulmonary bypass was applied as a protective measure during carotid endarterectomy.
Related Concept Videos
Decreased Body Temperature
Cardiopulmonary Resuscitation IV: Pharmacological Management

