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Obstructive jaundice secondary to multiple myeloma--a case report

Computerized Radiology : Official Journal of the Computerized Tomography Society
|July 1, 1986
PubMed

Insights

Multiple myeloma can rarely cause obstructive jaundice due to pancreatic head involvement. This case highlights a rare complication of this plasma cell malignancy.

Area of Science:

  • Oncology
  • Gastroenterology

Background:

  • Multiple myeloma is a plasma cell malignancy primarily affecting the bone marrow.
  • Pancreatic head involvement by extramedullary myeloma is exceptionally rare.

Observation:

  • A patient presented with obstructive jaundice, a clinical sign of biliary system blockage.
  • Diagnostic imaging revealed pancreatic head mass consistent with extramedullary myeloma.

Findings:

  • The patient's obstructive jaundice was directly caused by pancreatic head infiltration by multiple myeloma.
  • Literature review identified only three previously reported cases of this rare presentation.

Implications:

  • This case underscores the importance of considering extramedullary myeloma in the differential diagnosis of pancreatic head masses.
  • Increased awareness may improve early diagnosis and management of this rare myeloma complication.

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