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Updated: Sep 27, 2025

Spontaneous Murine Model of Anaplastic Thyroid Cancer
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USP26 promotes anaplastic thyroid cancer progression by stabilizing TAZ

Jianing Tang1, Yongwen Luo2, Liang Xiao3

  • 1Department of Liver Surgery, Xiangya Hospital, Clinical Research Center for Breast Cancer Control and Prevention in Hunan Province, Central South University, Changsha, China. tjn1995@whu.edu.cn.

Cell Death & Disease
|April 10, 2022
PubMed
Summary

Researchers found that USP26 deubiquitylase stabilizes TAZ protein in anaplastic thyroid cancer (ATC). Inhibiting USP26 reduced cancer cell growth and invasion, suggesting USP26 as a potential therapeutic target for aggressive ATC.

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