2D materials-based nanomedicine: From discovery to applications
Jiang Ouyang1, Siyuan Rao2, Runcong Liu3
1Center for Nanomedicine and Department of Anesthesiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Advanced Drug Delivery Reviews
|April 10, 2022
Summary
Two-dimensional (2D) materials show promise in nanomedicine for treating various diseases like cancer and infections. This review explores their biomedical applications, therapeutic potential, and future clinical translation.
Area of Science:
- Biomedical Engineering
- Materials Science
- Nanotechnology
Background:
- Two-dimensional (2D) materials possess unique physicochemical properties driving their increasing use in biomedicine.
- These materials are being explored for diverse applications, including cancer therapy, infection control, tissue engineering, and neurodegenerative disease treatment.
Purpose of the Study:
- To review the biomedical applications of 2D materials-based nanomedicines.
- To discuss the therapeutic and imaging potential, biological functionalization, and clinical prospects of these advanced nanomaterials.
Main Methods:
- Literature review focusing on the structures, characteristics, and applications of various 2D nanomaterials.
- Analysis of therapeutic mechanisms and functionalization strategies for 2D nanomedicines.
- Comprehensive summary of current and potential therapeutic uses across different diseases.
Main Results:
- Detailed introduction to typical 2D nanomaterials and their configurations.
- Discussion on the therapeutic and imaging capabilities, alongside biological functionalization of 2D nanomedicines.
- Summary of promising therapeutic applications in oncology, infectious diseases, and other critical health areas.
Conclusions:
- 2D materials-based nanomedicines offer significant therapeutic potential across a spectrum of diseases.
- Further research and development are crucial for overcoming challenges and achieving clinical translation of these innovative treatments.
