Related Experiment Video
Updated: Sep 27, 2025

Highly Sensitive and Rapid Fluorescence Detection with a Portable FRET Analyzer
Published on: October 1, 2016
An AIE fluorescent sensor for rapid and selective detection of phosgene
Li Da-Xue1, Li Dan1, Zong Liang1
1Institute of Chemical Defence, Beijing, 102205, China. wuwh2012@163.com.
Abstract:
Herein, an aggregation-induced emission (AIE)-based sensor, 4-(1,2,2-triphenylvinyl)benzoxime (TPE-phos), has been rationally designed for phosgene detection. The sensor has a tetraphenylethylene unit combined with an oxime moiety. TPE-phos undergoes nitrile formation after the oxime group reacts with phosgene, which will give a significant "light-up" fluorescence due to the AIE effect within seconds.
Related Concept Videos
Gas Chromatography: Types of Detectors-II
Fluorescence and Phosphorescence: Instrumentation
Photoluminescence: Applications
Atomic Fluorescence Spectroscopy
Labeling DNA Probes
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...
Reporter Genes

