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Related Experiment Video

Updated: Sep 27, 2025

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Published on: February 6, 2021

Resolution of Isolated Subretinal Abscess with Systemic Antibiotic Treatment.

Beatrice Gallo¹, Ilaria Testi¹, Gerry Clare¹

¹Uveitis Service, Moorfields Eye Hospital, London, UK.

Ocular Immunology and Inflammation

|April 11, 2022

Summary

This summary is machine-generated.

This study highlights a rare case of isolated subretinal abscess (SRA) in an otherwise healthy individual. Prompt antibiotic treatment led to successful resolution and vision preservation, underscoring the importance of early intervention for subretinal abscess.

Keywords:

Angiography endophthalmitis optical coherence tomography subretinal abscess systemic antibiotics

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Area of Science:

Ophthalmology
Infectious Diseases

Background:

Isolated subretinal abscess (SRA) is a rare condition, particularly in immunocompetent individuals without risk factors.
Understanding the clinical presentation and management of SRA is crucial for ophthalmologists.

Observation:

A case of unilateral focal SRA was observed in a 40-year-old immunocompetent male patient.
Systemic investigations ruled out any extraocular infective source.

Findings:

Prompt diagnosis and aggressive systemic antibiotic therapy were initiated.
The treatment successfully averted vitreous cavity breakthrough, leading to clinical resolution and preserved visual acuity.
No local recurrences or distal spread were noted during follow-up.

Implications:

Timely systemic antibiotic treatment is effective for isolated SRA, yielding excellent clinical outcomes.
Close monitoring is vital to prevent progression to sight-threatening endophthalmitis and guide therapeutic adjustments.