Related Experiment Video

Updated: Sep 27, 2025

Quantified Assessment of Infant's Gross Motor Abilities Using a Multisensor Wearable
09:24

Quantified Assessment of Infant's Gross Motor Abilities Using a Multisensor Wearable

Published on: May 17, 2024

1.6K

Early Motor Repertoire of Very Preterm Infants and Relationships with 2-Year Neurodevelopment

Amanda K-L Kwong1,2,3, Roslyn N Boyd1,4, Mark D Chatfield1,4

  • 1Queensland Cerebral Palsy and Rehabilitation Research Centre, Child Health Research Centre, Faculty of Medicine, The University of Queensland, Brisbane, QLD 4101, Australia.

Journal of Clinical Medicine
|April 12, 2022
PubMed

Insights

The revised Motor Optimality Score (MOS-R) effectively predicts neurodevelopmental outcomes in very preterm infants. This assessment tool shows strong relationships with cerebral palsy and motor/cognitive delays at two years corrected age.

Area of Science:

  • Neonatal Neurology
  • Developmental Pediatrics
  • Neurodevelopmental Assessment

Background:

  • Preterm infants (<31 weeks’ gestational age) face significant neurodevelopmental risks.
  • Early identification of neurodevelopmental impairments is crucial for timely intervention.
  • The Motor Optimality Score, revised (MOS-R) is an extension of the Prechtl General Movements Assessment, offering potential for early prediction.

Purpose of the Study:

  • To determine the relationship between the MOS-R and 2-year neurodevelopmental outcomes in very preterm infants.
  • To examine the predictive validity of the MOS-R at 3–4 months’ corrected age (CA) for neurodevelopmental outcomes.
  • To assess MOS-R's predictive power beyond established perinatal risk factors, including Prechtl fidgety movements.

Main Methods:

  • A cohort of 169 infants born very preterm (<31 weeks’ gestational age) was studied.
  • The MOS-R was administered at 3–4 months’ corrected age (CA).
  • Neurodevelopmental outcomes at 2 years’ CA were assessed using the Bayley Scales of Infant and Toddler Development, Third edition (Bayley-III) and the Neurological, Sensory, Motor, Developmental Assessment (NSMDA). Cerebral palsy (CP) was classified at 2 years.

Main Results:

  • The MOS-R demonstrated significant relationships with 2-year neurodevelopmental outcomes, including Bayley-III motor and cognitive scores, and NSMDA scores.
  • Each 1-point increase in MOS-R was associated with reduced odds of definite and clinical cerebral palsy.
  • A MOS-R score ≤ 23 effectively predicted motor impairment (sensitivity 78%) and neurosensory motor impairment (sensitivity 86%) at 2 years.

Conclusions:

  • The MOS-R is strongly associated with cerebral palsy and motor/cognitive delays at 2 years in very preterm infants.
  • The MOS-R serves as a valuable predictor of motor and neurosensory motor impairment in this high-risk population.
  • The MOS-R provides a reliable tool for early neurodevelopmental assessment in very preterm infants.

Keywords:
cognitive impairmentgeneral movementsmotor impairmentmotor optimality scoreneurodevelopmentpreterm infant

More Related Videos

A Novel Experimental and Analytical Approach to the Multimodal Neural Decoding of Intent During Social Interaction in Freely-behaving Human Infants11:14

A Novel Experimental and Analytical Approach to the Multimodal Neural Decoding of Intent During Social Interaction in Freely-behaving Human Infants

Published on: October 4, 2015

11.1K
Clinical Practice Protocol of Creative Music Therapy for Preterm Infants and Their Parents in the Neonatal Intensive Care Unit11:50

Clinical Practice Protocol of Creative Music Therapy for Preterm Infants and Their Parents in the Neonatal Intensive Care Unit

Published on: January 7, 2020

26.8K

Related Concept Videos

Language Development01:22

Language Development

Children master language quickly and with relative ease, supported by both biological predisposition and reinforcement. B. F. Skinner (1957) proposed that language is learned through reinforcement, while Noam Chomsky (1965) argued that language acquisition mechanisms are biologically determined.
The critical period for language acquisition suggests that the ability to acquire language is at its peak early in life. As people age, this proficiency decreases. Language development begins very...
494
Socioemotional Development during Infancy01:30

Socioemotional Development during Infancy

Socio-emotional development in infancy is primarily shaped by early emotional responses and social connections, with temperament playing a central role. Temperament refers to the consistent patterns in an individual's emotional and behavioral responses, observable even in infancy. By examining temperament, researchers can better understand an infant's unique ways of interacting with the world, influencing subsequent personality and socio-emotional growth.
Primary Temperament Types
172
Piaget's Stage 1 of Cognitive Development01:14

Piaget's Stage 1 of Cognitive Development

The sensorimotor stage, the initial phase of Jean Piaget's theory of cognitive development, spans the first two years of a child's life. During this period, infants actively engage with their surroundings, building cognitive awareness through direct interaction with the world. This interaction is primarily based on sensory perception and motor actions, allowing infants to gradually understand basic physical properties and predict how objects interact within their environment.
Exploration...
887
The Nativist Approach01:21

The Nativist Approach

The nativist approach to infant cognitive development proposes that infants are born with inherent knowledge structures that allow them to interpret the world almost immediately. This perspective contrasts with earlier developmental theories, such as those proposed by Jean Piaget, which emphasized a more gradual acquisition of cognitive abilities through interaction with the environment. One key concept in this approach is object permanence — the understanding that objects continue to...
161