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Related Concept Videos

Appendicitis-II: Diagnostic Studies and Management01:29

Appendicitis-II: Diagnostic Studies and Management

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Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
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Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
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Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

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The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
738
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

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Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
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Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

384
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
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Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

434
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
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One appendix too many: a severe IBD-U case in remission after appendectomy.

Pedro Bernardes Antunes1, Margarida Gonçalves1, Tiago Leal1

  • 1Gastroenterology , Hospital de Braga, Portugal.

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Summary

A woman developed inflammatory bowel disease unclassified (IBD-U) after childbirth, experiencing severe symptoms like bloody diarrhea and weight loss. Diagnostic colonoscopy revealed erosive inflammation throughout the ileum and colon.

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Area of Science:

  • Gastroenterology
  • Immunology
  • Internal Medicine

Background:

  • Inflammatory Bowel Disease Unclassified (IBD-U) presents a diagnostic challenge, often mimicking Crohn's disease or ulcerative colitis.
  • Post-partum onset of gastrointestinal symptoms requires careful evaluation for underlying inflammatory conditions.

Observation:

  • A 39-year-old female presented with chronic bloody diarrhea and significant weight loss in the post-partum period.
  • Clinical presentation suggested a severe inflammatory process affecting the lower gastrointestinal tract.

Findings:

  • Colonoscopy revealed extensive erosive inflammation in the terminal ileum (ileitis) and the entire colon (pancolitis).
  • Histopathological examination of biopsies confirmed chronic ileocolitis, consistent with IBD-U.

Implications:

  • This case highlights the importance of considering IBD-U in women presenting with severe gastrointestinal symptoms post-partum.
  • Accurate diagnosis of IBD-U is crucial for appropriate management and to prevent long-term complications.
  • Further research into the specific triggers and pathogenesis of post-partum IBD-U is warranted.