Related Experiment Video

Updated: Sep 27, 2025

Investigating von Willebrand Factor Pathophysiology Using a Flow Chamber Model of von Willebrand Factor-platelet String Formation
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Investigating von Willebrand Factor Pathophysiology Using a Flow Chamber Model of von Willebrand Factor-platelet String Formation

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Hyperadhesive von Willebrand Factor Promotes Extracellular Vesicle-Induced Angiogenesis: Implication for LVAD-Induced

Mengchen Yang1,2, Katie L Houck1, Xinlong Dong1

  • 1Bloodworks Research Institute, Seattle, Washington, USA.

JACC. Basic to Translational Science
|April 12, 2022
PubMed

Keywords:
ADAMTS-13:Ag, ADAMTS-13 antigenAVS, aortic vascular segmentEC, endothelial cellEV, extracellular vesicleEVFP, extracellular vesicle–free plasmaGI, gastrointestinalGOF, gain of functionGP, glycoproteinGPM, growth factor-poor mediumGRM, growth factor-rich mediumHSS, high shear stressLVAD, left ventricular assist devicePS, phosphatidylserineSIPA, shear-induced platelet aggregationULVWF, ultra-large von Willebrand factorVEGF, vascular endothelial growth factorVWF, von Willebrand factorVWF:Ag, von Willebrand factor antigenVWF:CB, von Willebrand factor binding to collagenVWF:pp, von Willebrand factor propeptideaVWS, acquired von Willebrand syndromeangiogenesisextracellular vesiclesleft ventricular assist devicespEV, extracellular vesicle from von Willebrand factor-activated plateletsplateletsshear stressvon Willebrand factor

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