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Vitamin D in infancy and childhood: factors determining vitamin D status

Advances in Pediatrics
|January 1, 1986
PubMed

Insights

Vitamin D and calcium metabolism are influenced by various factors in infants and children. Their bodies possess remarkable adaptability to maintain calcium balance during rapid growth and development.

Area of Science:

  • Pediatric Nutrition
  • Mineral Metabolism
  • Developmental Physiology

Background:

  • Vitamin D and calcium are crucial for skeletal development and overall health in infants and children.
  • Factors like gestational age, maternal influences, diet, and environment significantly impact nutrient metabolism.
  • The unique physiological demands of growth in early life present challenges to maintaining mineral homeostasis.

Purpose of the Study:

  • To explore the multifaceted factors influencing vitamin D and calcium metabolism in infants and children.
  • To understand the physiological adaptations enabling calcium homeostasis during critical developmental periods.
  • To highlight the importance of these factors for healthy skeletal development.

Main Methods:

  • Review of existing literature on pediatric vitamin D and calcium metabolism.
  • Analysis of factors affecting nutrient absorption and utilization in early life.
  • Examination of the regulatory systems maintaining calcium balance.

Main Results:

  • Gestational age, age, race, sex, maternal factors, diet, and environment all play a role in vitamin D and calcium metabolism.
  • The interplay of these factors is complex and still under investigation in pediatric populations.
  • Infants and children exhibit significant adaptability in managing calcium homeostasis.

Conclusions:

  • The vitamin D and calcium regulatory system in infants and children is highly adaptable.
  • Understanding these metabolic influences is key to optimizing skeletal growth and development.
  • Further research is needed to fully elucidate these complex interactions in pediatric health.

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