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Updated: Sep 27, 2025

Manufacturing Abdominal Aorta Hydrogel Tissue-Mimicking Phantoms for Ultrasound Elastography Validation
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Combined Curvature and Wall Shear Stress Analysis of Abdominal Aortic Aneurysm: An Analysis of Rupture Risk Factors

Biyun Teng1, Zhijun Zhou1, Yu Zhao1

  • 1Department of Vascular Surgery, The First Affiliated Hospital of Chongqing Medical University, No. 1, Youyi Road, Yuanjiagang, Yuzhong District, Chongqing, 400016, China.

Cardiovascular and Interventional Radiology
|April 13, 2022
PubMed

Insights

Abdominal aortic aneurysm rupture risk can be assessed using geometric and hemodynamic factors. Increased aneurysm curvature and reduced wall shear stress are key indicators of rupture risk.

Area of Science:

  • Cardiovascular Research
  • Biomedical Engineering
  • Medical Imaging Analysis

Background:

  • Abdominal aortic aneurysms (AAAs) pose a significant rupture risk.
  • Predicting AAA rupture remains a clinical challenge, necessitating advanced analytical methods.

Purpose of the Study:

  • To investigate the relationship between geometric and hemodynamic parameters and the risk of abdominal aortic aneurysm rupture.
  • To identify key predictors of AAA rupture using computational fluid dynamics.

Main Methods:

  • Retrospective analysis of computed tomography angiography (CTA) data from 35 patients with AAAs.
  • Application of computational fluid dynamics (CFD) to analyze anatomical factors and hemodynamic parameters.
  • Comparison of parameters between ruptured and unruptured AAA groups.

Main Results:

  • Significant differences observed in maximum diameter, curvature, and wall shear stress between ruptured and unruptured AAA groups.
  • Maximum diameter and curvature were significantly associated with AAA rupture.
  • Curvature demonstrated a negative correlation with wall shear stress.

Conclusions:

  • Both aneurysm curvature and wall shear stress are valuable in assessing AAA rupture risk.
  • Aneurysm curvature can serve as a geometric surrogate for wall shear stress in risk evaluation.
Abstract

Keywords:
Abdominal aortic aneurysmComputational fluid dynamicsCurvatureWall shear stress

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