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Updated: Sep 27, 2025

Quantitation of Endothelial Cell Adhesiveness In Vitro
Published on: June 18, 2015
Evolutionary adaptation highlights the interconnection of fatty acids, sunlight, inflammation and epithelial adhesion
Leslea J Hlusko1,2, Madeline G McNelis2
1National Research Center on Human Evolution (CENIEH), Burgos, Spain.
Abstract:
Gene variants that influence human biology today reflect thousands of years of evolution. Genetic effects on infant health are a major point of selective pressure, given that childhood survival is essential to evolutionary success. Knowledge of this evolutionary history can have implications for paediatric research. CONCLUSION: An episode of human adaptation to the extremely low ultraviolet radiation environment of the Arctic 20,000 years ago implicates the Ectodysplasin A Receptor (EDAR) and the Fatty Acid Desaturases (FADS) in human lactation and epithelial inflammation.
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