Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Skin Cancer01:30

Skin Cancer

4.8K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
4.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Fine-Needle Aspiration of Parotid Gland Sialoblastoma. Two New Cases and Literature Review.

Diagnostic cytopathology·2025
Same author

Reporting Bone Cytopathology-A Proposal Based on a Single Tertiary Centre Experience.

Cytopathology : official journal of the British Society for Clinical Cytology·2024
Same author

Cytology of a parietal swelling in a 52-year-old man.

Cytopathology : official journal of the British Society for Clinical Cytology·2023
Same author

Pitfalls in soft tissue cytopathology.

Cytopathology : official journal of the British Society for Clinical Cytology·2023
Same author

Interventional and EBUS cytology in Sweden.

Seminars in diagnostic pathology·2022
Same author

Comparative cytological and histological assessment of 828 primary soft tissue and bone lesions, and proposal for a system for reporting soft tissue cytopathology.

Cytopathology : official journal of the British Society for Clinical Cytology·2020

Related Experiment Video

Updated: Sep 27, 2025

Tumorsphere Derivation and Treatment from Primary Tumor Cells Isolated from Mouse Rhabdomyosarcomas
09:21

Tumorsphere Derivation and Treatment from Primary Tumor Cells Isolated from Mouse Rhabdomyosarcomas

Published on: September 13, 2019

7.3K

The Small Round Cell Sarcomas Complexities and Desmoplastic Presentation.

Henryk A Domanski1

  • 1Department of Clinical Genetics and Pathology, Laboratory Medicine Region Skåne, Lund, Sweden.

Acta Cytologica
|April 13, 2022
PubMed
Summary
This summary is machine-generated.

Small round cell sarcomas (SRCSs) are common pediatric cancers with overlapping features. Accurate diagnosis of these bone and soft tissue tumors relies on combining fine needle aspiration (FNA) biopsy with ancillary tests, even for rare presentations.

Keywords:
CytologyFine needle aspirationRound cellSarcomaSoft tissue

More Related Videos

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
08:57

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Published on: May 17, 2024

2.2K
Isolation and Characterization of Tumor-initiating Cells from Sarcoma Patient-derived Xenografts
07:18

Isolation and Characterization of Tumor-initiating Cells from Sarcoma Patient-derived Xenografts

Published on: June 13, 2019

7.1K

Related Experiment Videos

Last Updated: Sep 27, 2025

Tumorsphere Derivation and Treatment from Primary Tumor Cells Isolated from Mouse Rhabdomyosarcomas
09:21

Tumorsphere Derivation and Treatment from Primary Tumor Cells Isolated from Mouse Rhabdomyosarcomas

Published on: September 13, 2019

7.3K
Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
08:57

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Published on: May 17, 2024

2.2K
Isolation and Characterization of Tumor-initiating Cells from Sarcoma Patient-derived Xenografts
07:18

Isolation and Characterization of Tumor-initiating Cells from Sarcoma Patient-derived Xenografts

Published on: June 13, 2019

7.1K

Area of Science:

  • Oncology
  • Pathology
  • Pediatric Medicine

Background:

  • Small round cell sarcomas (SRCSs) represent a significant portion of pediatric solid malignancies.
  • These tumors exhibit heterogeneous clinical and overlapping microscopic features, complicating initial diagnosis.
  • SRCSs include entities like desmoplastic small round cell tumor, poorly differentiated synovial sarcoma, and alveolar rhabdomyosarcoma.

Purpose of the Study:

  • To review cytomorphologic criteria for small round cell sarcomas (SRCSs).
  • To highlight rare and divergent cytological features of SRCSs.
  • To emphasize the importance of ancillary tests in diagnosing SRCSs.

Main Methods:

  • Review of cytomorphologic criteria for SRCSs.
  • Analysis of clinical presentation, cytological features, immunohistochemical patterns, and molecular alterations.
  • Evaluation of fine needle aspiration (FNA) biopsy specimens in conjunction with ancillary tests.

Main Results:

  • SRCSs often require ancillary tests due to overlapping features.
  • Fine needle aspiration (FNA) biopsy, when combined with ancillary tests, enables accurate diagnosis in most cases.
  • Subtle cytologic features can narrow differential diagnoses and guide ancillary testing.

Conclusions:

  • Accurate diagnosis of SRCSs necessitates a comprehensive assessment of clinical, cytological, immunohistochemical, and molecular data.
  • Awareness of rare and divergent cytological findings is crucial to prevent misdiagnosis.
  • The role of FNA biopsy in diagnosing bone and soft tissue tumors is increasingly vital, supported by ancillary testing.