Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Factors Influencing Heart Rate01:30

Factors Influencing Heart Rate

5.1K
The heart rate, or pulse rate, is a vital indicator of cardiovascular health. It reflects the number of times the heart beats per minute. Various physiological and environmental factors influence heart rate, increasing or decreasing cardiac output. Understanding these factors is crucial for assessing heart function and identifying potential health issues.
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
5.1K
Cardiac Output I:Effect of Heart Rate on Cardiac Output01:19

Cardiac Output I:Effect of Heart Rate on Cardiac Output

1.5K
Cardiac Output
Cardiac output (CO) refers to the total amount of blood ejected by one of the ventricles in liters per minute (L/min). In a resting adult, CO ranges from 5 to 6 L/min, adjusting according to the body's metabolic requirements.
Effect of Heart Rate on Cardiac Output
Cardiac output adapts to metabolic demands during stress, physical activity, or illness. The autonomic nervous system regulates heart rate via the sinoatrial node. The parasympathetic nervous system decreases heart...
1.5K
Factors Affecting Respiration01:24

Factors Affecting Respiration

7.7K
Respiration is a crucial physiological function involving exchanging oxygen (O2) and carbon dioxide (CO2) between an organism and its environment. Various factors can impact this essential process:
7.7K
Exercise and Cardiac Output01:17

Exercise and Cardiac Output

1.3K
Regular physical activity is essential for maintaining cardiovascular health, with aerobic exercises being particularly effective. According to the American Heart Association, 150 minutes of moderate to intense aerobic exercise per week is recommended for a healthy heart. Aerobic activities may include brisk walking, running, bicycling, cross-country skiing, and swimming, ideally performed three to five times per week.
Sustained exercise increases the muscles' oxygen demand, which can be...
1.3K
Regulation of Heart Rates01:31

Regulation of Heart Rates

2.3K
The regulation of heart rate is a complex process controlled by the autonomic nervous system (ANS), hormonal influences, and intrinsic cardiac mechanisms. The ANS has two main components: the sympathetic nervous system (SNS) and the parasympathetic nervous system (PNS).
The SNS increases heart rate through the release of norepinephrine and epinephrine, which act on beta-1 adrenergic receptors in the heart. This action increases the rate of depolarization in the sinoatrial (SA) node, the heart's...
2.3K
Exercise and Cardiovascular Response01:20

Exercise and Cardiovascular Response

1.1K
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
1.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The PADS atrial fibrillation/flutter prediction score: more evidence needed.

European journal of preventive cardiology·2023
Same author

Reliability of Biomarkers of Physiological Stress at Rest and Post-exertional Heat Stress.

International journal of sports medicine·2022
Same author

Perioperative Management of Pulmonary Hypertension. a Review.

Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures)·2021
Same author

Relationship between coronary microvascular dysfunction and left ventricular diastolic function in patients with chest pain and unobstructed coronary arteries.

Echocardiography (Mount Kisco, N.Y.)·2020
Same author

Iron bioavailability and cardiopulmonary function during ascent to very high altitude.

The European respiratory journal·2020
Same author

The Effects of Apnea Training, Using Voluntary Breath Holds, on High Altitude Acclimation: Breathe-High Altitude Study.

High altitude medicine & biology·2020

Related Experiment Video

Updated: Sep 27, 2025

Calculating Heart Rate Variability from ECG Data from Youth with Cerebral Palsy During Active Video Game Sessions
08:12

Calculating Heart Rate Variability from ECG Data from Youth with Cerebral Palsy During Active Video Game Sessions

Published on: June 5, 2019

20.0K

The Effect of High-Altitude Acclimatisation on Ultra-Short Heart Rate Variability.

Christopher John Boos1,2,3, Adrian Mellor3,4,5, David Richard Woods4,6,7

  • 1Department of Cardiology, Poole Hospital, University Hospitals Dorset, Poole, United Kingdom.

Frontiers in Cardiovascular Medicine
|April 14, 2022
PubMed
Summary

High-altitude exposure alters heart rate variability (HRV) similarly for both ultra-short and standard 300-second measurements. These HRV methods show moderate agreement but do not predict acute mountain sickness.

Keywords:
acclimatisationacute mountain sicknessheart rate variabilityhigh-altitudeoxygen saturation

More Related Videos

Author Spotlight: Investigating HR-Dependent Cardiac Function in Mouse Models Through a Novel Atrial-Pacing Approach
07:49

Author Spotlight: Investigating HR-Dependent Cardiac Function in Mouse Models Through a Novel Atrial-Pacing Approach

Published on: July 21, 2023

1.6K
Autonomic Function Following Concussion in Youth Athletes: An Exploration of Heart Rate Variability Using 24-hour Recording Methodology
05:48

Autonomic Function Following Concussion in Youth Athletes: An Exploration of Heart Rate Variability Using 24-hour Recording Methodology

Published on: September 21, 2018

10.2K

Related Experiment Videos

Last Updated: Sep 27, 2025

Calculating Heart Rate Variability from ECG Data from Youth with Cerebral Palsy During Active Video Game Sessions
08:12

Calculating Heart Rate Variability from ECG Data from Youth with Cerebral Palsy During Active Video Game Sessions

Published on: June 5, 2019

20.0K
Author Spotlight: Investigating HR-Dependent Cardiac Function in Mouse Models Through a Novel Atrial-Pacing Approach
07:49

Author Spotlight: Investigating HR-Dependent Cardiac Function in Mouse Models Through a Novel Atrial-Pacing Approach

Published on: July 21, 2023

1.6K
Autonomic Function Following Concussion in Youth Athletes: An Exploration of Heart Rate Variability Using 24-hour Recording Methodology
05:48

Autonomic Function Following Concussion in Youth Athletes: An Exploration of Heart Rate Variability Using 24-hour Recording Methodology

Published on: September 21, 2018

10.2K

Area of Science:

  • Physiology
  • Altitude Medicine
  • Cardiovascular Health

Background:

  • High-altitude (HA) exposure impacts heart rate variability (HRV), but its effect on ultra-short HRV and correlation with standard measures at HA remains unclear.
  • Acute mountain sickness (AMS) has inconsistent links to HRV, necessitating further investigation into HRV's predictive capabilities.

Purpose of the Study:

  • To investigate the influence of increasing HA exposure on ultra-short HRV.
  • To examine the relationship between ultra-short HRV and gold standard HRV measures at HA.
  • To determine if HRV measurements can predict AMS.

Main Methods:

  • Prospective observational study of adults trekking in the Himalayas.
  • Collected cardiac inter-beat intervals using 10-second (supra-systolic BP) and 300-second (ECG) recordings.
  • Measured HRV (RMSSD) at sea level and altitudes of 3,619m, 4,600m, and 5,140m; analyzed agreement using Bland-Altman analysis.

Main Results:

  • Both 10-second and 300-second RMSSD initially increased at 3,619m but significantly decreased at higher altitudes (4,600m and 5,140m).
  • A moderate correlation (Spearman r = 0.66) was found between 10-second and 300-second RMSSD measurements.
  • 92.4% of paired HRV values fell within the limits of agreement; neither HRV method predicted AMS.

Conclusions:

  • Increasing HA affects ultra-short HRV similarly to standard 300-second measurements.
  • Ultra-short HRV demonstrates moderate agreement with 300-second measurements at HA.
  • HRV measurements, by either method, were not found to be predictive of AMS.