Related Experiment Video
Updated: Sep 27, 2025

Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint
Published on: July 22, 2021
[Osteotomy close to the knee joint in adults]
Markus Heinecke1, Georg Matziolis2
1Deutsches Zentrum für Orthopädie, Waldkliniken Eisenberg mit Professur für Orthopädie der Friedrich-Schiller-Universität Jena, Klosterlausnitzer Str. 81, 07607, Eisenberg, Deutschland. m.heinecke@waldkliniken-eisenberg.de.
Abstract:
Osteotomy close to the knee joint in cases of axial deformities or in the context of corrective interventions is still an elementary component of the spectrum of orthopedic surgery. The precise localization and analysis of the pathology are crucial in order to restore approximate physiological loading conditions by means of a suitable osteotomy procedure. Thus, above all, the medial open-wedge tibial osteotomy has become established as a standard procedure for the treatment of knee osteoarthritis caused by extra-articular tibial varus deformity. Furthermore, corrective osteotomy of the sagittal axis of the tibia and of the distal femur also show good long-term results when the indications are correctly interpreted. The osteotomies described in this article are corrections that should be performed after careful consideration of the biological and mechanical aspects. Correct planning, attention to risk factors and the surgical technique are the main factors that determine the long-term success of the procedure.
Related Concept Videos
Knee Joint
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris...
Bones of the Lower Limb: Femur and Patella
Ankle Joint
Muscles that Move the Leg
Anterior Compartment
The quadriceps femoris, the most visible muscle of the anterior compartment, is integral for leg extension and thigh flexion. It is formed by merging four distinct muscles — the vastus lateralis, vastus medialis, vastus intermedius, and rectus femoris. The quadriceps tendon, a shared tendon of the four quadriceps muscles, is affixed...

