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Updated: Sep 27, 2025

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota
Published on: July 31, 2019
Pectic polysaccharides: Targeting gut microbiota in obesity and intestinal health
Hye-Bin Lee1, Young-Soo Kim2, Ho-Young Park3
1Food Functionality Research Division, Korea Food Research Institute, Jeollabuk-do 55365, Republic of Korea; Department of Food Science and Technology, Jeonbuk National University, Jeollabuk-do 54896, Republic of Korea.
Abstract:
The gut microbiome is a complex ecosystem of the host body that maintains a balance with its host. In this context, dysbiosis can lead to inflammatory response, immune dysregulation, and various metabolic disorders. Dietary polysaccharides mediate gut microbiota and its metabolites related to host health. In this review, we describe the structural characteristics of pectic polysaccharides and the functional correlation between their structure-specific characteristics and the modulatory activity of gut microbiota. We also discuss the health benefits of pectic polysaccharides on diet-induced obesity and intestinal health based on their source and structure. By regulating gut microbiota, pectic polysaccharides exert a wide range of biological effects, including the inhibition of obesity, fatty liver disease, and inflammation, and the increase in gut barrier function and immune-enhancing activity. This review expected to serve as a valuable resource to further clarity the relationship between pectic polysaccharides and gut microbiota.
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