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Acute Post-Cataract Endophthalmitis Due to Phialemoniopsis curvata: A Rare Case Report

Mengli Tang1, Jun Li1,2, Fengjun Xia1

  • 1Department of Clinical Laboratory, Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China.

Infection and Drug Resistance
|April 15, 2022
PubMed

Insights

Phialemoniopsis curvata, a fungus rarely causing eye infections, led to acute post-cataract endophthalmitis. Prompt treatment with voriconazole successfully alleviated the patient's symptoms.

Area of Science:

  • Medical Mycology
  • Infectious Diseases
  • Ophthalmology

Background:

  • Phialemonium species are opportunistic fungi causing various invasive infections.
  • Endophthalmitis is a rare clinical manifestation of Phialemonium infections.
  • Environmental fungi pose risks to immunocompromised and even immunocompetent individuals.

Observation:

  • A rare case of acute post-cataract endophthalmitis was reported in China.
  • The causative agent was identified as Phialemoniopsis curvata through microscopy, culture, and sequencing.
  • The patient presented with symptoms following cataract surgery.

Findings:

  • Phialemoniopsis curvata was successfully isolated and identified from the patient's eye.
  • The fungal infection manifested as acute endophthalmitis after cataract surgery.
  • Microscopic, cultural, and molecular methods confirmed the pathogen's identity.

Implications:

  • This case highlights Phialemoniopsis curvata as a potential cause of rare but severe ocular infections.
  • Early diagnosis and appropriate antifungal treatment (voriconazole) are crucial for managing Phialemoniopsis-induced endophthalmitis.
  • Further research into Phialemonium species and their ocular pathogenicity is warranted to improve clinical outcomes.
Keywords:
Phialemoniopsis curvatacataract surgeryfungal endophthalmitisvoriconazole

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