Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ziegler–Natta Chain-Growth Polymerization: Overview01:17

Ziegler–Natta Chain-Growth Polymerization: Overview

3.5K
Ziegler–Natta polymerization is another form of addition or chain‐growth polymerization used for synthesizing linear polymers over branched polymers. The catalyst used for polymerization is the Ziegler–Natta catalyst, named after Karl Ziegler and Giulio Natta, who developed it in 1953. This catalyst is an organometallic complex of titanium tetrachloride and triethyl aluminum, with the active form of the catalyst being an alkyl titanium compound. Using the Ziegler–Natta...
3.5K
Anionic Chain-Growth Polymerization: Mechanism01:04

Anionic Chain-Growth Polymerization: Mechanism

2.1K
The mechanism for anionic chain-growth polymerization involves initiation, propagation, and termination steps. In the initiation step, a nucleophilic anion, such as butyl lithium, initiates the polymerization process by attacking the π bond of the vinylic monomer. As a result, a carbanion, stabilized by the electron‐withdrawing group, is generated. The resulting carbanion acts as a Michael donor in the propagation step and attacks the second vinylic monomer, which acts as a Michael...
2.1K
Cationic Chain-Growth Polymerization: Mechanism00:57

Cationic Chain-Growth Polymerization: Mechanism

2.4K
The cationic polymerization mechanism consists of three steps: initiation, propagation, and termination. In the initiation step of the polymerization process, the π bond of a monomer gets protonated by the Lewis acid catalyst, which is formed from boron trifluoride and water. The protonation of the π bond generates a carbocation stabilized by the electron‐donating group. In the propagation step, the π bond of the second monomer acts as a nucleophile and attacks the...
2.4K
Anionic Chain-Growth Polymerization: Overview01:20

Anionic Chain-Growth Polymerization: Overview

2.2K
The polymerization process that involves carbanion as an intermediate is called anionic polymerization. It is also a type of addition or chain-growth polymerization. Anionic polymerization gets initiated by a strong nucleophile such as an organolithium or a Grignard reagent. The most commonly used initiator for anionic polymerization is butyl lithium. Monomers involved in anionic polymerization must possess a vinyl group bonded to one or two electron-withdrawing groups. For instance,...
2.2K
Formation of Intermediate Filaments00:57

Formation of Intermediate Filaments

3.2K
Intermediate filaments are cytoskeletal proteins with higher tensile strength and flexibility than microfilaments and microtubules. Unlike the other two cytoskeletal proteins, intermediate filament formation lacks the enzymatic activity to hydrolyze nucleotides like ATP and GTP to generate energy for polymerization. Therefore, the formation of intermediate filaments is multistep self-assembly. The involvement of any accessory proteins in intermediate filament formation has not yet been...
3.2K
Actin Polymerization01:42

Actin Polymerization

7.1K
Actin polymerization occurs through the head-to-tail association of binding sites on monomeric actin or G-actin to form filamentous or F-actin. The polymerization can be divided into three phases ̶  nucleation, elongation, and steady-state phase.
The nucleation phase involves forming a stable nucleus consisting of three actin monomers to form a new actin filament. Actin-binding proteins such as formins and Arp2/3 complex help filament growth post-nucleation. The Formins form straight...
7.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Self-Immunoregulatory Nanosensitizer for Sonodynamic Cancer Therapy.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

A Self-Cascading Immunomodulatory Hydrogel for Remodeling Infected Diabetic Wounds.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

Synergistic Chemoimmunotherapy of Hepatocellular Carcinoma via ROS-Responsive Carrier-Free Prodrug Nanoparticles.

Nano letters·2026
Same author

Copper Depletion Nanoparticles Potentiate Cancer Immunotherapy by Avoiding Innate and Adaptive Immune Resistance.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

Multifunctional ruthenium-based complexes for chronic wound therapy: from ligand engineering to intelligent microenvironment remodeling.

Nanoscale·2026
Same author

A Near-Infrared Off-On Fluorescent Probe for Sensitive and Specific Imaging of Fibroblast Activation Protein-α Activity in Pancreatic Cancer.

Luminescence : the journal of biological and chemical luminescence·2026

Related Experiment Video

Updated: Sep 27, 2025

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives
09:22

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives

Published on: February 7, 2017

7.9K

Constructing helical nanowires via polymerization-induced self-assembly.

Qiumeng Chen1, Yahui Li1, Ming Liu1

  • 1State Key Laboratory of Ophthalmology, Optometry and Vision Science, School of Ophthalmology and Optometry, School of Biomedical Engineering, Wenzhou Medical University Wenzhou 325027 PR China.

RSC Advances
|April 15, 2022
PubMed
Summary
This summary is machine-generated.

Researchers developed a new method for creating helical block copolymer (BCP) nanowires using polymerization-induced self-assembly (PISA). This strategy enables the production of ultralong helical structures from achiral BCPs, offering a versatile approach for materials science.

More Related Videos

Ultrahigh Density Array of Vertically Aligned Small-molecular Organic Nanowires on Arbitrary Substrates
08:07

Ultrahigh Density Array of Vertically Aligned Small-molecular Organic Nanowires on Arbitrary Substrates

Published on: June 18, 2013

15.2K
DNA Nanotubes as a Versatile Tool to Study Semiflexible Polymers
08:00

DNA Nanotubes as a Versatile Tool to Study Semiflexible Polymers

Published on: October 25, 2017

7.0K

Related Experiment Videos

Last Updated: Sep 27, 2025

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives
09:22

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives

Published on: February 7, 2017

7.9K
Ultrahigh Density Array of Vertically Aligned Small-molecular Organic Nanowires on Arbitrary Substrates
08:07

Ultrahigh Density Array of Vertically Aligned Small-molecular Organic Nanowires on Arbitrary Substrates

Published on: June 18, 2013

15.2K
DNA Nanotubes as a Versatile Tool to Study Semiflexible Polymers
08:00

DNA Nanotubes as a Versatile Tool to Study Semiflexible Polymers

Published on: October 25, 2017

7.0K

Area of Science:

  • Polymer Chemistry
  • Materials Science
  • Nanotechnology

Background:

  • Block copolymer (BCP) nanowires are valuable nanostructures, but helical variants are challenging to synthesize.
  • Polymerization-induced self-assembly (PISA) is a powerful technique for BCP nanostructure formation.
  • Existing PISA methods rarely yield helical nanowire morphologies.

Purpose of the Study:

  • To develop a novel strategy for synthesizing helical BCP nanowires via PISA.
  • To investigate the role of a fluorinated stabilizer block in mediating helical self-assembly.
  • To demonstrate the generality and applicability of the new method across different BCP compositions and monomers.

Main Methods:

  • Utilized PISA mediated by a specifically designed fluorinated stabilizer block.
  • Investigated the morphology transition of achiral BCP nano-objects during aging.
  • Expanded the range of monomers and block compositions to test the strategy's generality.

Main Results:

  • Successfully produced ultralong nanowires with a distinct helical structure.
  • Achieved morphology transition from spheres to helical nanowires upon aging.
  • Demonstrated the method's effectiveness with various monomer types and block compositions.

Conclusions:

  • A new, general strategy for constructing helical BCP nanowires via PISA has been established.
  • The fluorinated stabilizer block is key to mediating the helical morphology.
  • This work provides a versatile route for synthesizing helical nanostructures from achiral BCPs.