Optimization of through-time radial GRAPPA with coil compression and weight sharing

This work proposes principal component analysis (PCA) coil compression and weight sharing to reduce acquisition and reconstruction time of through-time radial GRAPPA.

Through-time radial GRAPPA enables ungated free-breathing motion-resolved cardiac imaging but requires a long calibration acquisition and GRAPPA weight calculation time. PCA coil compression reduces calibration data requirements and associated acquisition time, and weight sharing reduces the number of unique GRAPPA weight sets and associated weight computation time. In vivo cardiac data reconstructed with coil compression and weight sharing are compared to a gold standard to demonstrate improvement in calibration acquisition and reconstruction performance with minimal loss of image quality.

Coil compression from 30 physical to 12 virtual coils (90% of signal variance) decreases requisite calibration data by 60%, reducing calibration acquisition time to 6.7 s/slice from 31.5 s/slice reported in original through-time radial GRAPPA work. Resulting images have small increase in RMS error (RMSE). Reconstruction with a weight sharing factor of 8 results in eight-fold reduction in GRAPPA weight calculation time with a comparable RMSE to reconstructions with no weight sharing. Optimized parameters for coil compression and weight sharing applied to reconstructions enables images to be collected with a temporal resolution of 66 ms/frame and spatial resolution of 2.34 × 2.34 mm while reducing calibration acquisition time from 34 to 6.7 s, weight calculation time from 200 to 3 s, and weight application time 18 to 5 s.

Coil compression and weight sharing applied to through-time radial GRAPPA enables fast free-breathing ungated cardiac cine without compromising image quality.