The Cancer Research Database (CRDB): Integrated Platform to Gain Statistical Insight Into the Correlation Between...

Area of Science:

• Oncology
• Bioinformatics
• Genomics
• Data Science

Background:

• Cancer research relies on accessible literature, databases, and tools.
• The COVID-19 pandemic highlighted the need for data sharing and cooperation in genomics and big data research.
• Existing cancer research databases are difficult to access due to fragmented data management.

Purpose of the Study:

• To develop an integrated cancer research database and platform for statistical analysis of cancer and COVID-19 correlations.
• To unify previously published cancer databases into a single, transparent platform.
• To score databases based on cancer type variety, sample size, omics completeness, and user interface.

Main Methods:

• Integrated 85 cancer databases including Data Portal, Genomic, Proteomic, Expression, Gene, and Mutation databases.
• Developed a unified database of databases named the Cancer Research Database (CRDB).
• Implemented unique navigation tools for browsing individual databases, categories, or all databases via search bar or clickable icons.

Main Results:

• The Cancer Research Database (CRDB) consolidates 85 cancer databases.
• CRDB provides a user-friendly interface with multiple browsing options for efficient information retrieval.
• CRDB facilitates a comprehensive analysis of cancer statistics and diagnoses during the COVID-19 pandemic.

Conclusions:

• The CRDB is a freely accessible, web-based computational platform built with PHP, HTML, CSS, and MySQL.
• The platform is designed for continuous updates to ensure relevance.
• CRDB provides a manageable and understandable framework for researchers to mine knowledge, particularly concerning cancer during the COVID-19 pandemic.