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Extremely low bispectral index value during robotic-assisted laparoscopic prostatectomy: A case report
1Department of Anaesthesiology and Critical Care Medicine, Ibaraki Clinical Education and Training Center, University of Tsukuba, Kasama, Ibaraki, Japan.
Saudi Journal of Anaesthesia
|April 18, 2022
Summary
Steep Trendelenburg position and pneumoperitoneum during surgery can cause significant decreases in the bispectral index (BIS), indicating reduced brain activity. Releasing these surgical conditions rapidly restored normal BIS values without neurological deficits.
Area of Science:
- Anesthesiology
- Neuroscience
- Surgical Technology
Background:
- The steep Trendelenburg position and pneumoperitoneum are common in robotic-assisted laparoscopic prostatectomy (RALP).
- These surgical conditions can potentially impact intracranial pressure, cerebral oxygenation, and cerebrovascular autoregulation.
- The bispectral index (BIS) is a measure of anesthetic depth and brain activity.
Observation:
- A case study involving a patient undergoing RALP experienced a significant decrease in BIS values 6 hours into the surgery.
- A concurrent decrease in the electroencephalography (EEG) suppression ratio (SR) was observed, suggesting reduced brain activity.
- The patient was managed under general anesthesia throughout the procedure.
Findings:
- The prolonged steep Trendelenburg position and pneumoperitoneum were associated with extremely low BIS values and decreased EEG suppression ratio.
- Upon release of the Trendelenburg position and termination of anesthesia, BIS values rapidly increased.
- The patient experienced no neurological deficits and was discharged following recovery.
Implications:
- Steep Trendelenburg positioning and pneumoperitoneum may induce electroencephalography (EEG) abnormalities, specifically manifesting as reduced BIS values.
- Anesthesiologists should be aware of the potential impact of these surgical maneuvers on brain activity monitoring.
- Further research may be warranted to understand the mechanisms and clinical significance of BIS changes in this context.

