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Updated: Sep 26, 2025

Comparing Objective Conjunctival Hyperemia Grading and the Ocular Surface Disease Index Score in Dry Eye Syndrome During COVID-19
Published on: May 25, 2022
Ocular manifestations of COVID-19
1Eye Research Center, LLC, 4023 Kennett Pike # 548, Wilmington, DE 19807, USA.
Insights
COVID-19 ocular symptoms like conjunctivitis are reported in adults. Further research on COVID-19 eye symptoms in children and the elderly is needed, alongside essential eye protection for healthcare professionals.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Public Health
Background:
- COVID-19, caused by SARS-CoV-2, emerged in December 2019.
- The pandemic led to millions of cases and deaths globally by May 2021.
- Ocular manifestations of COVID-19 require further investigation.
Purpose of the Study:
- To review current literature on COVID-19 ocular symptoms in adults, elderly, and children.
- To highlight necessary eye protection measures for clinical settings during the pandemic.
Main Methods:
- PubMed database search from December 2019 to May 2021.
- Inclusion of randomized trials, observational studies, case series/reports, and letters.
- Focus on articles reporting confirmed COVID-19 cases.
Main Results:
- Over 205 articles published since the COVID-19 outbreak.
- Reported ocular symptoms in adults include conjunctivitis, conjunctival hyperemia, and chemosis.
- Limited studies exist on ocular symptoms in pediatric and elderly populations.
Conclusions:
- Conjunctivitis is a recognized ocular symptom of COVID-19 in adults.
- More research is needed to understand COVID-19's impact on the eyes of children and the elderly.
- Mandatory use of eye protection is crucial for healthcare providers managing patients during the pandemic.
Abstract:
COVID-19 is a disease caused by a SARS-CoV-2 viral infection, a disease that was first detected in December 2019 in Wuhan, Hubei Province, China. COVID-19, formerly known as 2019 Novel Coronavirus (2019-nCoV) respiratory disease, was officially named COVID-19 by the World Health Organization (WHO) in February 2020. By 25 May 2021, there were 33,579,116 confirmed cases with 599,109 COVID-19 deaths worldwide. The purpose of this review article is to provide an update on what is currently known about COVID-19 ocular symptoms in adults, the elderly, and children in the literature. Finally, this article will review the eye protection precautions that should be implemented in our clinics. To assess the current literature, PubMed was searched from December 2019 to 25 May 2021. Randomized trials, observational studies, case series or case reports, letters of research, and letters to editors were selected for confirmed cases of COVID-19. According to current scientific literature since the outbreak in December 2019, 205 articles have been published. Conjunctivitis, conjunctival hyperemia, and chemosis have been reported in adults with COVID-19. There have been few studies on children and elderly patients, and further research in these age groups is needed. Finally, wearing eye protection when seeing patients on a daily basis during the pandemic is essential.
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