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A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound
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p63-positive prostate carcinoma-A very rare presentation
Sanjana B Lokesha1, Beshwanth V Chowdary2, Jyoti R Kini3
1Resident, 3rd year, MBBS, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Karnataka, India.
Indian Journal of Pathology & Microbiology
|April 18, 2022
Summary
This study reports a rare case of p63-positive prostate adenocarcinoma, a finding that challenges standard diagnostic markers for prostate cancer. Early detection and treatment are crucial for favorable outcomes.
Area of Science:
- Oncology
- Pathology
Background:
- Prostate cancer is a leading global cancer, presenting diagnostic challenges.
- Immunohistochemistry markers like high molecular weight cytokeratin (HMWCK) and p63 are vital for diagnosis.
- Typically, absence of p63/HMWCK and presence of p504s indicate malignancy.
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