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Related Concept Videos

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Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
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Subject-specific Musculoskeletal Model for Studying Bone Strain During Dynamic Motion
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A peridynamic formulation for nonlocal bone remodelling.

E Schaller1, A Javili2, I Schmidt3

  • 1Institute of Applied Mechanics, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.

Computer Methods in Biomechanics and Biomedical Engineering
|April 18, 2022
PubMed
Summary
This summary is machine-generated.

This study introduces a novel peridynamic formulation for macroscale bone remodeling, overcoming limitations of local continuum theory. The new model accurately simulates bone density evolution and nonlocality effects.

Keywords:
Bone remodellingdensity evolutioninfluence of nonlocalitynonlocal materialperidynamics

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Area of Science:

  • Biomechanics
  • Computational Solid Mechanics
  • Bone Physiology

Background:

  • Bone remodeling is a complex biomechanical process.
  • Previous studies were limited by local continuum theory.
  • A nonlocal framework is needed for a comprehensive understanding.

Purpose of the Study:

  • To propose the first macroscale peridynamic formulation for bone remodeling.
  • To investigate the influence of nonlocality on bone density evolution.
  • To validate the model using benchmark tests and proximal femur load cases.

Main Methods:

  • Development of a peridynamic formulation for bone remodeling at the macroscale.
  • Implementation and testing on a standard benchmark problem.
  • Application to two distinct load cases of the proximal femur.

Main Results:

  • Peridynamic model results converge to finite element model results as nonlocality diminishes.
  • Increasing neighborhood size in the peridynamic model demonstrates the impact of nonlocality on density evolution.
  • The model successfully simulates bone remodeling processes under various loading conditions.

Conclusions:

  • The proposed peridynamic formulation offers a viable nonlocal approach to bone remodeling.
  • Nonlocality is a significant factor influencing bone density evolution.
  • This framework advances the computational study of bone biomechanics.