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Comparison of Dentin Caries Remineralization with Four Bioactive Cements
S Valizadeh1,2, S S H Kamangar3, M H Nekoofar4,5
1Associate Professor, Dental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Dental Faculty of Tehran University of Medical Sciences, Tehran, Iran.
Summary
Bioactive cements show no significant difference in remineralizing dentin caries. While Biodentine had the highest mineral content, none of the tested cements formed hydroxyapatite crystals in adjacent dentin.
Area of Science:
- Dentistry
- Biomaterials Science
- Mineralization Studies
Background:
- Deep carious lesions require treatments that promote dentin remineralization.
- Ion-releasing agents are utilized to seal lesions and release minerals.
- Bioactive cements offer potential for enhanced remineralization.
Purpose of the Study:
- To compare the dentin caries remineralization efficacy of four bioactive cements.
- To evaluate mineral content and crystal formation adjacent to tested materials.
Main Methods:
- Artificial caries were induced in human dentin blocks via pH cycling.
- Blocks were treated with Dycal, Oxford ActiveCal PC, Biodentine, ACTIVA Bioactive, or no cement (control).
- Samples underwent 30-day storage in remineralization solution, followed by analysis using Energydispersive X-ray Spectroscopy and X-ray Diffraction.
Main Results:
- No significant differences in calcium and phosphorus weight percentages or Ca:P ratios were found between groups.
- Biodentine exhibited the highest mineral content, while the control group showed the lowest.
- None of the bioactive cements induced hydroxyapatite crystal formation in the adjacent dentin.
Conclusions:
- The tested bioactive cements demonstrated comparable, non-significant remineralization effects on dentin caries.
- Further research is needed to enhance the hydroxyapatite-forming capabilities of these materials for improved caries management.
