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Updated: Sep 26, 2025

A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones

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Indole Editing Enabled by HFIP-Mediated Ring-Switch Reactions of 3-Amino-2-Hydroxyindolines

Takumi Abe1, Toshiki Yamashiro1, Kaho Shimizu1

  • 1Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 1-1-1 Tsushima-naka, Kita-ku, Okayama, 7008530, Japan.

Chemistry (Weinheim an Der Bergstrasse, Germany)
|April 19, 2022
PubMed

Keywords:
HFIPhemiaminalsindolesmolecule editingring-switch

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