The relationship between short-term PM_2.5 exposure and outpatient visits for acne vulgaris in Chongqing, China: a...

Many researches have reported the air pollution impacts, either long term or short term, on inflammatory skin diseases, but there are few studies on the relation between PM_2.5 and acne vulgaris. To determine the correlation between short-term PM_2.5 exposure and acne outpatient visits, data for 120,842 acne vulgaris outpatient visits between December 2013 and December 2019 were obtained from three large hospitals in Chongqing, China. Both single-pollutant models and two-pollutant models were established to explore the relationship between PM_2.5 exposure and acne outpatient visits. The stratified analyses were conducted through two-sample z-tests to investigate the possible gender (male or female) and age (< 25 years or ≥ 25 years) differences in PM_2.5 effects. The results demonstrated positive correlations between PM_2.5 concentrations and acne outpatient visits. A 10 μg/m³ increase in PM_2.5 concentration was associated with a 1.71% (95% CI: 1.06-2.36%) increase in acne outpatient visits at lag 0-7 day. Stratified analyses showed that PM_2.5 effects were greater in individuals aged ≥ 25 years than those aged < 25 years, but no gender difference was found. In conclusion, short-term PM_2.5 exposure was positively associated with the risk of acne outpatient visits, especially for people ≥ 25 years old.