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Related Experiment Video

Updated: Jul 11, 2026

Murine Fetal Echocardiography

Murine Fetal Echocardiography

Published on: February 15, 2013

Fetal Hand Abnormalities in the First-Trimester Scan: A Report of Two Cases.

Emmanouil Katsanevakis¹, Caterina Tzitzikalakis², Natalia Karagioti³

¹Obstetrics and Gynecology, United Lincolnshire Hospitals NHS Trust, Lincoln, GBR.

|April 21, 2022

Summary

Early first-trimester diagnosis of fetal hand abnormalities like syndactyly and polydactyly enables genetic testing and appropriate management, including pregnancy termination when necessary.

Keywords:

early anomaly scan fetal abnormalities fetal medicine first trimester scan polydactyly syndactyly

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Last Updated: Jul 11, 2026

Murine Fetal Echocardiography

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Published on: February 15, 2013

Fetal Mouse Cardiovascular Imaging Using a High-frequency Ultrasound 30/45MHZ System

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Published on: December 16, 2022

Area of Science:

Medical diagnostics
Prenatal screening
Fetal medicine

Background:

Fetal hand abnormalities can indicate underlying genetic conditions or developmental issues.
Early detection is crucial for informed decision-making and management.

Observation:

Two cases highlight the significance of first-trimester scans for identifying fetal anomalies.
Case 1: Unilateral fetal syndactyly led to early diagnosis of a severe genetic condition.
Case 2: Bilateral hand polydactyly with a cardiac defect, incompatible with life, was also detected early.

Findings:

First-trimester routine scans facilitated the early diagnosis of complex fetal hand malformations.
Invasive testing confirmed genetic conditions associated with syndactyly.
Combined anomalies in the second case were incompatible with extrauterine existence.

Implications:

Early detection of fetal hand abnormalities allows for timely genetic counseling and intervention.
Appropriate management, including early pregnancy termination, can be offered when severe conditions are identified.
Advances in first-trimester screening improve prenatal care and patient outcomes.