Prenatal substance use policies and newborn health

Angélica Meinhofer1, Allison Witman2, Johanna Catherine Maclean3

  • 1Department of Population Health Sciences, Weill Cornell Medicine, New York, New York, USA.

Health Economics
|April 21, 2022
PubMed

Insights

Punitive policies on prenatal substance use increase neonatal drug withdrawal syndrome. Supportive treatment policies improve perinatal health outcomes, including reduced low birth weight and gestational age.

Area of Science:

  • Public Health
  • Health Policy
  • Perinatal Health

Background:

  • Policies addressing illicit substance use during pregnancy vary significantly.
  • Understanding the impact of these policies on maternal and infant outcomes is crucial for public health.
  • Existing research has not fully elucidated the differential effects of punitive versus supportive approaches.

Purpose of the Study:

  • To examine the effects of punitive and priority treatment policies on neonatal drug withdrawal syndrome, birth weight, gestational age, and prenatal care.
  • To compare the outcomes associated with criminalizing prenatal substance use versus providing priority access to treatment.

Main Methods:

  • Utilized administrative data from 2008 to 2018.
  • Employed a difference-in-differences empirical strategy to analyze the staggered implementation of policies.
  • Focused on key perinatal health indicators: neonatal drug withdrawal syndrome, low birth weight, low gestational age, and prenatal care use.

Main Results:

  • Punitive policies were associated with a 10%-18% increase in neonatal drug withdrawal syndrome.
  • Punitive policies led to modest reductions in prenatal care use, potentially due to healthcare avoidance.
  • Priority treatment policies showed small reductions (2%) in low gestational age and low birth weight, with increased prenatal care use.

Conclusions:

  • Punitive policies regarding prenatal substance use may lead to adverse perinatal outcomes.
  • Supportive, priority treatment policies appear more effective in improving perinatal health.
  • Policy recommendations should favor supportive approaches to enhance maternal and infant well-being.

Related Concept Videos

Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
231
Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics01:23

Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics

Respiratory symptoms, such as congestion and cough, commonly accompany respiratory tract conditions. Various medications, such as antitussives, expectorants, and mucolytics, play crucial roles in providing relief.
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla.  Benzonatate operates peripherally within the respiratory tract by...
486
Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
2.9K
Factors Affecting Drug Response: Overview01:21

Factors Affecting Drug Response: Overview

When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily because their organ functions still need to fully develop, meaning their bodies are not as efficient at metabolizing or eliminating drugs. Additionally, their blood-brain barrier is more permeable than in adults. As a result, high concentrations of drugs can easily penetrate the central nervous system (CNS), potentially leading to neurological...
2.4K
Drug Regulation01:25

Drug Regulation

Drug regulation encompasses the management of drug usage by evaluating its safety and efficacy through assessments conducted by regulatory authorities. Regrettably, the history of drug regulation is marred by several catastrophic events. One such incident is the Elixir Sulfanilamide tragedy, in which the toxic compound diethyl glycol was included in a sweet-tasting medication, leading to numerous fatalities. This event prompted the enactment of the Food, Drug, and Cosmetic Act in 1938. Under...
1.9K
Physiological Barriers01:25

Physiological Barriers

Physiological barriers are semi-permeable cellular structures restricting drug diffusion into intracellular compartments and tissues. There are six types of physiological barriers: blood endothelial, cell membrane, blood-brain, blood-cerebrospinal fluid (CSF), blood-placenta, and blood-testis barriers.
The blood endothelial barrier is the most porous of these. It allows all small ionized, un-ionized, and lipophilic molecules to pass through the endothelial lining into the interstitial space...
4.3K