A Polyniobotungstate-Based Hybrid for Visible-Light-Induced Phosphorylation of N-Aryl-Tetrahydroisoquinoline

A new organic-inorganic hybrid based on a Nb/W mixed-addendum polyoxometalate with the formula H₁₄[(Co(H₂O)₃)₂(C₁₀H₈N₂)₄(P₄W₃₀Nb₆O₁₂₃)]·4(C₁₀H₈N₂)·8H₂O (Co-POM) has been synthesized by the solvothermal method and characterized by single-crystal X-ray diffraction (XRD), powder X-ray diffraction (PXRD), elemental analysis, FTIR spectroscopy, UV-vis absorption spectrum, and thermogravimetric analysis (TGA). Importantly, visible-light-absorption peaks around 525 nm for Co-POM indicated that this material should have potential in visible-light-induced organic reactions. Herein, we disclosed visible-light-promoted phosphorylation of N-aryl-tetrahydroisoquinoline using Co-POM as an efficient heterogeneous photocatalyst. In this procedure, diverse phosphorus reagents are compatible at room temperature and in an O₂ atmosphere, giving the corresponding products in good to excellent yields (up to 97%). Simultaneously, this heterogeneous photocatalyst can be recycled up to ten times with a negligible decrease in yield, showing outstanding sustainability and recyclability.