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Published on: July 23, 2016
DEXAMETHASONE INTRAVITREAL IMPLANT COMPLICATIONS INCLUDING VITREOUS HEMORRHAGE AND HYPOTONY
1Department of Ophthalmology, Kellogg Eye Center, University of Michigan, Ann Arbor, Michigan; and.
Purpose:
To describe cases of visually significant vitreous hemorrhage (VH) following dexamethasone intravitreal implant in our practice and present two cases that required surgical intervention and a case of VH and hypotony following dexamethasone implant. An injection technique that may minimize the incidence of these complications is described and illustrated.
Methods:
Retrospective case series.
Results:
The overall incidence of VH was 1.7% (8 of 467 injections) and those that required surgical intervention was 0.4% (2/467) over a 10-year period, from June 2010 to June 2020 ( Table 1 ). Overall, 75% (6 of 8) VH resolved spontaneously over time, without surgical intervention.
Conclusion:
Nonclearing VH and hypotony are rare but serious complications of dexamethasone implant.
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