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Related Concept Videos

Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

216
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
216
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

452
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
452
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

477
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
477
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

340
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
340
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

254
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
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Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

478
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
478

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Author Spotlight: Induction of Experimental Endotoxemic Shock in Pigs for Studying Hemodynamic and Respiratory Failure
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Tuberculosis-Associated Septic Shock: A Case Series.

Veerendra Arya1, Amarendra K Shukla2, Brahma Prakash3

  • 1General Medicine, School of Excellence in Pulmonary Medicine, Netaji Subhash Chandra Bose Medical College, Jabalpur, IND.

Cureus
|April 22, 2022
PubMed
Summary
This summary is machine-generated.

Tuberculosis septic shock (TBSS) is a rare condition. This case series highlights the clinical characteristics, comorbidities, and outcomes of six patients with TBSS, emphasizing the importance of early diagnosis and treatment for improved survival.

Keywords:
intensive caretb presenting as shocktbsstuberculosistuberculosis septic shock

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Area of Science:

  • Infectious Diseases
  • Critical Care Medicine
  • Pulmonology

Background:

  • Tuberculosis septic shock (TBSS) is an uncommon clinical presentation of tuberculosis (TB).
  • Diagnostic challenges and attribution to other causes contribute to its rarity.
  • Understanding TBSS is crucial for timely intervention in severe TB cases.

Purpose of the Study:

  • To describe the clinical characteristics, comorbidities, hospital course, and outcomes of patients diagnosed with TBSS.
  • To identify factors associated with TBSS and its in-hospital mortality.
  • To raise awareness of this rare but severe manifestation of tuberculosis.

Main Methods:

  • Retrospective case series analysis of six patients diagnosed with TBSS.
  • Data collection included patient demographics, comorbidities, clinical presentation, diagnostic methods, treatment, and outcomes.
  • Severity assessed using the APACHE II score.

Main Results:

  • The median age of patients was 54.5 years, with a majority having comorbidities like diabetes mellitus.
  • Microbiologic confirmation of tuberculosis was achieved through various methods, including respiratory secretions and abscess aspirates.
  • The in-hospital mortality rate was 16.7%, with most patients successfully discharged after treatment.

Conclusions:

  • Tuberculosis septic shock, though rare, presents a significant challenge in critically ill patients.
  • Prompt diagnosis and appropriate antitubercular therapy are essential for managing TBSS.
  • Further research is needed to elucidate the pathophysiology and optimize management strategies for TBSS.