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Updated: Sep 26, 2025

Modeling Neonatal Intraventricular Hemorrhage Through Intraventricular Injection of Hemoglobin
Published on: August 25, 2022
Pathogenesis and prevention of intraventricular hemorrhage
Aisling A Garvey1, Brian H Walsh2, Terrie E Inder3
1Department of Pediatric Newborn Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Abstract:
Despite improvements in the mortality rates of preterm infants, rates of germinal matrix intraventricular hemorrhage (IVH) have remained static with an overall incidence of 25% in infants less than 32 weeks. The importance of the lesion relates primarily to the underlying injury to the developing brain and the associated long-term neurodevelopmental consequences. This clinical-orientated review focuses on the pathogenesis of IVH and discusses the evidence behind proposed prevention strategies.
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