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Related Concept Videos

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Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
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DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
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Related Experiment Video

Updated: Sep 26, 2025

A Magnetic Resonance Imaging Protocol for Stroke Onset Time Estimation in Permanent Cerebral Ischemia
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Interobserver Reliability on Intravoxel Incoherent Motion Imaging in Patients with Acute Ischemic Stroke.

K Yamashita1, R Kamei2, H Sugimori3

  • 1From the Departments of Radiology (K.Y., R.K., K.F., S.H., J.M., T.N.) yamakou@radiol.med.kyushu-u.ac.jp.

AJNR. American Journal of Neuroradiology
|April 22, 2022
PubMed
Summary

Intravoxel incoherent motion MR imaging provides reliable perfusion information for acute ischemic stroke assessment. This noninvasive technique shows good interobserver agreement and aids in evaluating treatment strategies.

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Area of Science:

  • Radiology
  • Neuroimaging
  • Medical Physics

Background:

  • Noninvasive perfusion imaging aids in identifying the ischemic penumbra for acute ischemic stroke (AIS) treatment.
  • Intravoxel incoherent motion (IVIM) MR imaging offers rapid, noninvasive perfusion assessment.

Purpose of the Study:

  • To evaluate the interobserver agreement of IVIM MR imaging parameters.
  • To assess the clinical utility of IVIM MR imaging in patients with AIS.

Main Methods:

  • Retrospective study of 29 AIS patients using 1.5T MR imaging with IVIM sequences.
  • Acquisition of diffusion coefficient, perfusion fraction, and pseudodiffusion coefficient maps using a 2-step fitting algorithm.
  • Interobserver agreement assessed using the κ statistic for IVIM parameter maps.

Main Results:

  • Almost perfect agreement (κ = 0.854) for IVIM perfusion fraction maps.
  • Substantial agreement (κ = 0.789) for IVIM pseudodiffusion coefficient maps.
  • Non-decreased IVIM perfusion fraction correlated with higher rates of arterial recanalization.

Conclusions:

  • IVIM MR imaging is a rapid (<1 minute) and feasible tool for qualitative perfusion assessment in AIS.
  • IVIM parameters provide valuable, noninvasive perfusion-related information for clinical decision-making in AIS.
  • This technique supports the evaluation of penumbral regions and treatment strategies.