Related Experiment Video

Updated: Sep 26, 2025

A Magnetic Resonance Imaging Protocol for Stroke Onset Time Estimation in Permanent Cerebral Ischemia
09:59

A Magnetic Resonance Imaging Protocol for Stroke Onset Time Estimation in Permanent Cerebral Ischemia

Published on: September 16, 2017

14.2K

Interobserver Reliability on Intravoxel Incoherent Motion Imaging in Patients with Acute Ischemic Stroke

K Yamashita1, R Kamei2, H Sugimori3

  • 1From the Departments of Radiology (K.Y., R.K., K.F., S.H., J.M., T.N.) yamakou@radiol.med.kyushu-u.ac.jp.

AJNR. American Journal of Neuroradiology
|April 22, 2022
PubMed
Abstract

Insights

Intravoxel incoherent motion MR imaging provides reliable perfusion information for acute ischemic stroke assessment. This noninvasive technique shows good interobserver agreement and aids in evaluating treatment strategies.

Area of Science:

  • Radiology
  • Neuroimaging
  • Medical Physics

Background:

  • Noninvasive perfusion imaging aids in identifying the ischemic penumbra for acute ischemic stroke (AIS) treatment.
  • Intravoxel incoherent motion (IVIM) MR imaging offers rapid, noninvasive perfusion assessment.

Purpose of the Study:

  • To evaluate the interobserver agreement of IVIM MR imaging parameters.
  • To assess the clinical utility of IVIM MR imaging in patients with AIS.

Main Methods:

  • Retrospective study of 29 AIS patients using 1.5T MR imaging with IVIM sequences.
  • Acquisition of diffusion coefficient, perfusion fraction, and pseudodiffusion coefficient maps using a 2-step fitting algorithm.
  • Interobserver agreement assessed using the κ statistic for IVIM parameter maps.

Main Results:

  • Almost perfect agreement (κ = 0.854) for IVIM perfusion fraction maps.
  • Substantial agreement (κ = 0.789) for IVIM pseudodiffusion coefficient maps.
  • Non-decreased IVIM perfusion fraction correlated with higher rates of arterial recanalization.

Conclusions:

  • IVIM MR imaging is a rapid (<1 minute) and feasible tool for qualitative perfusion assessment in AIS.
  • IVIM parameters provide valuable, noninvasive perfusion-related information for clinical decision-making in AIS.
  • This technique supports the evaluation of penumbral regions and treatment strategies.

More Related Videos

Author Spotlight: Integrated Photoacoustic, Ultrasound, and Angiographic Tomography (PAUSAT) for NonInvasive Whole-Brain Imaging of Ischemic Stroke06:45

Author Spotlight: Integrated Photoacoustic, Ultrasound, and Angiographic Tomography (PAUSAT) for NonInvasive Whole-Brain Imaging of Ischemic Stroke

Published on: June 2, 2023

1.8K
Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping10:25

Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping

Published on: September 25, 2019

48.5K

Related Concept Videos

Imaging Studies for Cardiovascular System IV: CMRI01:21

Imaging Studies for Cardiovascular System IV: CMRI

Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
145
Imaging Studies IV: Magnetic Resonance Imaging01:27

Imaging Studies IV: Magnetic Resonance Imaging

Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
63
Imaging Studies VII: Vascular Imaging01:19

Imaging Studies VII: Vascular Imaging

DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
79
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
138
Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
7.4K