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Updated: Sep 26, 2025
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Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
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A South Africa tertiary centre experience with redo mitral valve replacement
D Kistan1, M Booysen1, G Alexander2
1Department of General Surgery, University of KwaZulu-Natal, South Africa.
Summary
Mechanical mitral valve thrombosis often necessitates emergency redo mitral valve replacement (MVR). This study highlights outcomes of redo MVR in South Africa, finding a 3.1% mortality rate and 15.6% complication rate.
Area of Science:
- Cardiovascular Surgery
- Mechanical Heart Valves
- Thrombosis Management
Background:
- Mechanical mitral valve thrombosis is a significant cause of emergency redo mitral valve replacement (MVR) in South Africa.
- Poor warfarin control is a primary driver of this complication.
- This study reviews outcomes of redo MVR in patients presenting with mitral valve failure.
Purpose of the Study:
- To review the outcomes of emergency and elective redo mitral valve replacement (MVR) procedures.
- To identify the primary aetiologies and patient demographics for redo MVR.
- To assess postoperative complications and mortality rates.
Main Methods:
- Retrospective chart review of patients undergoing redo MVR between 2005 and 2014.
- Analysis of patient demographics, aetiology of valve dysfunction, and clinical outcomes.
- Evaluation of 64 patients undergoing 80 mitral valve procedures.
Main Results:
- Rheumatic valve disease was the original pathology in 90.6% of patients.
- Prosthetic valve thrombosis was present in 73.8% of emergency redo procedures.
- The postoperative mortality rate was 3.1%, with a 15.6% complication rate.
Conclusions:
- Redo MVR is frequently an emergency procedure, primarily driven by valve thrombosis.
- The study reports a 3.1% mortality and 15.6% complication rate for redo MVR.
- Findings underscore the critical need for effective anticoagulation management in mechanical mitral valve patients.
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