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Assessment of the Rectum and Anus01:25

Assessment of the Rectum and Anus

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Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
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Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
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Drugs for Treatment of Constipation-Predominant IBS01:21

Drugs for Treatment of Constipation-Predominant IBS

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Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
357
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

549
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
549
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

376
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
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Drugs for Treatment of Diarrhea-Predominant IBS01:17

Drugs for Treatment of Diarrhea-Predominant IBS

332
Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
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Related Experiment Video

Updated: Sep 26, 2025

A Mouse Model of Intestinal Partial Obstruction
07:33

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Rectal Polyposis in Mucosal Prolapse Syndrome.

Yin Ping Wong1, Connie Kabincong1, Mohd Faisal Jabar2

  • 1Department of Pathology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia.

Diagnostics (Basel, Switzerland)
|April 23, 2022
PubMed
Summary

Mucosal prolapse syndrome, also known as solitary rectal ulcer syndrome, can mimic various rectal polyps and lesions. This condition presents diagnostic challenges due to overlapping features, requiring careful histological examination.

Keywords:
histological mimicsmucosal prolapserectal polyp

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Area of Science:

  • Gastroenterology
  • Pathology
  • Colorectal Surgery

Background:

  • Mucosal prolapse syndrome (MPS), or solitary rectal ulcer syndrome, is a condition that can present as rectal ulcerations or polyps.
  • It often mimics other colorectal pathologies, posing diagnostic challenges for clinicians and pathologists.
  • Common symptoms include rectal bleeding, and it affects individuals across a wide age range, including children.

Observation:

  • This report details two cases of MPS presenting as rectal polyposis.
  • The gross and histological features of MPS can overlap with other lesions, complicating diagnosis.
  • Characteristic histological findings include fibromuscular obliteration of the lamina propria and splayed, hypertrophic muscularis mucosae.

Findings:

  • The study highlights the diagnostic difficulties in differentiating MPS from other polypoid lesions.
  • Key histological features are crucial for accurate identification of MPS.
  • The differential diagnosis for rectal polyposis must include MPS.

Implications:

  • Accurate diagnosis of MPS is essential to avoid misclassification and ensure appropriate management.
  • Understanding the histological nuances of MPS aids in distinguishing it from neoplastic polyps.
  • This case series contributes to the literature on MPS presentation and its diagnostic considerations.