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The Concept of Postbiotics.

Gabriel Vinderola1, Mary Ellen Sanders2, Seppo Salminen3

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Summary
This summary is machine-generated.

Postbiotics, or inanimate microorganisms and their components, offer health benefits. The International Scientific Association for Probiotics and Prebiotics (ISAPP) defined postbiotics in 2021, encouraging innovation in human and animal health applications.

Keywords:
ISAPPInternational Scientific Association for Probiotics and Prebioticsheat-inactivated probioticsinanimatemicroorganismsnon-viable probioticspostbioticsprobiotics

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Area of Science:

  • Microbiology
  • Nutrition Science
  • Health Sciences

Background:

  • Various terms like paraprobiotics and ghostbiotics have been used for inanimate microorganisms conferring health benefits.
  • The International Scientific Association for Probiotics and Prebiotics (ISAPP) proposed a definition for postbiotics in 2021.
  • Postbiotics are defined as preparations of inanimate microorganisms or their components that provide health benefits.

Purpose of the Study:

  • To analyze the characteristics of different definitions of postbiotics.
  • To highlight the comprehensive nature of the ISAPP definition.
  • To discuss the potential of postbiotics in various health applications.

Main Methods:

  • Literature review of existing definitions and terminology for postbiotics.
  • Analysis of the ISAPP 2021 definition and its implications.
  • Discussion of technological perspectives and health benefits.

Main Results:

  • The ISAPP definition requires inactivated microbes or their components, with or without metabolic products.
  • This definition is broad, encompassing various microorganisms and applications.
  • It encourages innovation across human, animal, and plant health sectors.

Conclusions:

  • The ISAPP definition of postbiotics is comprehensive and promotes innovation.
  • Postbiotics represent a promising area for health and therapeutic applications.
  • Further research is needed to establish the health contributions of inanimate microbial components.