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A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
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Contrast-Associated Acute Kidney Injury

Alessandro Mandurino-Mirizzi1, Andrea Munafò1, Gabriele Crimi2,3

  • 1Division of Cardiology, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy.

Journal of Clinical Medicine
|April 23, 2022
PubMed

Insights

Contrast-associated acute kidney injury (CA-AKI) is a kidney function decline after contrast dye. This review covers CA-AKI

Area of Science:

  • Nephrology
  • Cardiology
  • Radiology

Background:

  • Minimally invasive cardiac interventions are rising.
  • Contrast-associated acute kidney injury (CA-AKI) is a concern in these procedures.
  • Understanding CA-AKI is crucial for patient outcomes.

Purpose of the Study:

  • To review the epidemiology and risk factors of CA-AKI.
  • To outline diagnostic criteria and pathophysiology.
  • To present evidence on preventive strategies for CA-AKI.

Main Methods:

  • Literature review of CA-AKI studies.
  • Synthesis of data on epidemiology and risk stratification.
  • Analysis of diagnostic criteria and pathophysiology.
  • Evaluation of preventive measures.

Main Results:

  • CA-AKI affects renal function post-contrast media administration.
  • Increasing popularity of cardiac interventions heightens CA-AKI relevance.
  • Evidence-based preventive strategies are discussed.

Conclusions:

  • CA-AKI is a significant clinical issue.
  • Comprehensive understanding aids in risk management.
  • Further research into prevention is warranted.

Keywords:
acute kidney injurycontrast medianephropathy

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