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Effects of SARS-CoV-2 Inflammation on Selected Organ Systems of the Human Body

Marta Kopańska1, Edyta Barnaś2, Joanna Błajda2

  • 1Department of Pathophysiology, Institute of Medical Sciences, Medical College, University of Rzeszow, 35-959 Rzeszow, Poland.

International Journal of Molecular Sciences
|April 23, 2022
PubMed
Abstract

Insights

The SARS-CoV-2 virus can cause long-term multi-organ damage, affecting systems like the nervous and circulatory. Research indicates these complications may persist for over six months, impacting various bodily functions.

Area of Science:

  • Virology
  • Infectious Diseases
  • Public Health

Background:

  • The SARS-CoV-2 virus, responsible for COVID-19, extends its impact beyond the respiratory system.
  • Emerging evidence suggests potential long-term sequelae affecting multiple organ systems.

Purpose of the Study:

  • To review current research on the long-term effects of SARS-CoV-2 infection.
  • To assess the prevalence of these long-term symptoms and identify at-risk populations.

Main Methods:

  • A comprehensive literature review was conducted.
  • Included studies were sourced from PubMed and Web of Science databases.
  • Analysis encompassed 88 studies focusing on the long-term effects of SARS-CoV-2.

Main Results:

  • SARS-CoV-2 infection can lead to multi-organ damage with lasting health complications.
  • Long-term effects have been observed in the nervous, circulatory, respiratory, urinary, and reproductive systems.
  • These complications can manifest as significant functional disturbances in affected organs.

Conclusions:

  • Evidence suggests COVID-19 complications can persist for over six months.
  • Primary affected systems include the nervous, circulatory, and respiratory systems.
  • Current research is limited by small sample sizes and short study durations, with some findings being speculative.
Keywords:
COVID-19human bodylong-term effectsmulti-organ damage

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