Chitosan-salicylide Schiff base with aggregation-induced emission property and its multiple applications

Aggregation-induced emission (AIE) active compounds are fascinated due to their unique properties of limiting intramolecular rotation, and they have been developed in the biomedical fields. In this work, AIE material based on the Schiff base compound of chitosan (Cs) and salicylaldehyde (SA) was designed and synthesized. Cs-SA emits weak light in dilute aqueous solution, and emits bright light in concentrated solution and solid, showing obvious AIE performance. In addition, Cs-SA can also be used as a biosensor to detect Fe³⁺, and Cu²⁺, it has good bioimaging behavior. In addition, it can also be used as biosensor to quantitatively detect gram-positive bacteria and gram-negative bacteria, Moreover, Cs-SA shows excellent broad spectrum antibacterial performance in inhibiting E. coli and S. aureus.