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Updated: Sep 26, 2025
08:51
The Use of Thermal Infra-Red Imaging to Detect Delayed Onset Muscle Soreness
Published on: January 22, 2012
19.4K
A biosensor based on a thermal camera using infrared radiance as the signal probe
Fu Jiao1, Fengjing Cao2, Yuan Gao2
1National Research Center of Intelligent Equipment for Agriculture, Beijing Academy of Agriculture and Forestry Sciences, Beijing, 100097, China; Guangxi Key Laboratory of Intelligent Control and Maintenance of Power Equipment, Guangxi University, Nanning, 530004, China.
Talanta
|April 24, 2022
Summary
This study introduces a novel biosensor using infrared radiance, not true temperature, for sensitive detection. Smartphone-based thermal cameras enable portable, in-pocket sensing of biomarkers like human IgG.
Area of Science:
- Biosensor technology
- Biomarker detection
- Infrared thermography
Background:
- Flexible signal probes are advancing biosensor applications.
- Temperature-based signal probes offer a novel research direction.
- Current methods measure true temperature, influenced by emissivity.
Purpose of the Study:
- To develop a novel biosensing method using infrared radiance as the signal probe.
- To convert immunoassay signals into measurable infrared radiation.
- To create portable and flexible biosensor readout systems.
Main Methods:
- Designed a sensing method utilizing infrared radiance proportional to target amount.
- Controlled an aluminum plate at constant temperature for varied infrared radiation.
- Developed readout systems using scientific-grade and smartphone-based thermal cameras.
Main Results:
- Successfully detected human IgG biomarker in the 0-100 ng/mL range.
- Achieved a low detection limit of 0.54 ng/mL.
- Demonstrated excellent quantitative model performance.
Conclusions:
- The novel infrared radiance-based sensing method offers powerful detection capabilities.
- Smartphone-based thermal cameras provide a portable and flexible readout option.
- This approach advances the development of next-generation biosensors.
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