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Secretory Immunoglobulin A and Upper Cervical Chiropractic: A Preliminary Prospective, Multicenter, Observational
Philip R Schalow1, Kelly A Kimball2, Frederick T Schurger3
1Private practice, Rockford, Illinois.
Journal of Chiropractic Medicine
|April 25, 2022
Summary
Chiropractic care using upper cervical adjusting techniques (UCATs) temporarily boosts secretory immunoglobulin A (SIgA) levels. This immune marker returned to baseline after two weeks, indicating a short-term effect.
Area of Science:
- Immunology
- Chiropractic Medicine
- Craniocervical Junction Research
Background:
- Secretory immunoglobulin A (SIgA) is a crucial component of mucosal immunity.
- Upper cervical adjusting techniques (UCATs) are a specific form of chiropractic manipulation.
- The craniocervical junction (CCJ) is a complex anatomical area influencing neurological and physiological functions.
Purpose of the Study:
- To investigate the impact of UCATs on SIgA levels.
- To determine if chiropractic care affects immune markers.
- To explore the physiological responses to CCJ manipulation.
Main Methods:
- Saliva samples were collected from 41 participants before UCATs, 30 minutes after, and after 2 weeks.
- Participants received UCATs at the CCJ in a clinical setting.
- SIgA concentrations in saliva were analyzed.
Main Results:
- A statistically significant increase in SIgA was observed 30 minutes post-UCAT.
- SIgA levels returned to near baseline levels after a 2-week period.
- The study indicates a transient effect of UCATs on salivary SIgA.
Conclusions:
- UCATs at the CCJ induce a short-lived elevation in SIgA.
- Chiropractic interventions may have temporary immunomodulatory effects.
- Further research is needed to understand the mechanisms and clinical significance of these findings.
