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Published on: July 11, 2013
Listeria Meningitis in a Patient With Plaque Psoriasis on Ustekinumab Therapy
Moni Roy1,2, Naveen Vuppuluri3, Ashish K Roy2
1Internal Medicine, University of Illinois College of Medicine, Peoria, USA.
Abstract:
Listeria monocytogenes is a foodborne infection and is a leading cause of meningitis. The at-risk population includes patients over age 65, neonates, pregnant females, and patients with impaired cell immunity. Ustekinumab is a human monoclonal antibody that binds to and interferes with the proinflammatory cytokines, interleukin-12 (IL-12) and interleukin-23(IL-23). The drug is used for the treatment of Crohn's disease, ulcerative colitis, psoriatic arthritis, and plaque psoriasis. We present a case of listeria meningitis in a patient on ustekinumab therapy for plaque psoriasis.
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