Aggressive Multimodality Therapy for a Urachal Rhabdomyosarcoma

Area of Science:

• Pediatric Oncology
• Urologic Oncology

Background:

• Urachal rhabdomyosarcoma is a rare pediatric malignancy with a historically poor prognosis.
• Early detection and multimodal treatment are crucial for improving outcomes.

Observation:

• A 2-year-old male presented with abdominal pain, fatigue, and urinary frequency.
• Imaging and pathological examination confirmed primary embryonal rhabdomyosarcoma of the urachus.

Findings:

• The patient underwent upfront surgical resection followed by adjuvant chemoradiation.
• Treatment followed the Children's Oncology Group protocol D9803.

Implications:

• This case highlights a successful treatment approach for a rare and aggressive pediatric cancer.
• Multimodal therapy, including surgery and chemoradiation, can lead to favorable outcomes in urachal rhabdomyosarcoma.