Lichen planus pemphigoides: report of a case with oral lesions

Lichen planus pemphigoides is a rare condition characterized by the coexistence of lichen planus and bullous pemphigoid. Oral lesions have been reported but have not been studied immunopathologically. We describe a 59-year-old white man with cutaneous and oral lesions of lichen planus pemphigoides. Biopsies were done on these lesions, and the specimens were examined by routine light microscopy and immunofluorescent techniques. Fine keratotic striae on the anterior buccal mucosa were clinically consistent with oral lichen planus. Perilesional tissue associated with ulceration of the posterior buccal mucosa showed histologic and immunopathologic changes consistent with bullous pemphigoid.