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XePhIR: the zebrafish xenograft phenotype interactive repository
A Groenewoud1,2, G Forn-Cuní1, F B Engel2,3
1Institute of Biology Leiden, Animal Sciences, Leiden University, Einsteinweg 55, CC Leiden 2333, The Netherlands.
Database : the Journal of Biological Databases and Curation
|April 28, 2022
Summary
The Xenograft Phenotype Interactive Repository (XePhIR) is a new platform for sharing zebrafish xenograft data. This resource aims to standardize protocols and enhance the reproducibility of cancer research using zebrafish models.
Area of Science:
- Cancer Biology
- Translational Research
Background:
- Zebrafish xenografts are a widely used model in cancer biology research.
- There is a lack of standardized protocols and data-sharing platforms for zebrafish xenograft phenotypes.
Purpose of the Study:
- To introduce the Xenograft Phenotype Interactive Repository (XePhIR) as an independent data-sharing platform.
- To standardize protocols and facilitate data sharing for zebrafish xenograft models.
- To enhance the visibility and reproducibility of research utilizing zebrafish xenografts.
Main Methods:
- Development of an independent data-sharing platform, XePhIR (https://www.xephir.org).
- Data deposition and sharing after the acceptance of original publications.
- Focus on standardizing protocols and sharing zebrafish xenograft phenotype data.
Main Results:
- XePhIR provides a dedicated resource for zebrafish xenograft data.
- The platform enhances the reach and visibility of original research articles.
- XePhIR aims to improve the reproducibility of studies using zebrafish xenografts.
Conclusions:
- XePhIR serves as a valuable resource for the cancer biology community.
- The platform promotes standardization and data sharing in zebrafish xenograft research.
- XePhIR will showcase the utility and applicability of zebrafish xenograft models in research.
