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A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
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Defining Neonatal Serious Illness.

Katherine Guttmann1, Amy Kelley2, Andrea Weintraub1

  • 1Division of Newborn Medicine, Department of Pediatrics, The Icahn School of Medicine at Mount Sinai, New York, New York, USA.

Journal of Palliative Medicine
|April 29, 2022
PubMed
Summary
This summary is machine-generated.

Defining neonatal serious illness is crucial for advancing palliative care research. This study developed a consensus definition incorporating mortality risk, lifelong complexity, and significant impact on patients and families.

Keywords:
definitionneonatalpalliative careserious illness

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Area of Science:

  • Neonatal Medicine
  • Palliative Care Research
  • Medical Ethics

Background:

  • Rigorous research in neonatal palliative care is hindered by the absence of universally agreed-upon definitions for key concepts.
  • Establishing a clear definition of neonatal serious illness is fundamental for advancing palliative care for neonates.

Purpose of the Study:

  • To develop a consensus-based conceptual definition of neonatal serious illness.
  • To provide a foundational definition for future research in neonatal palliative care.

Main Methods:

  • A two-round Delphi-like survey study was conducted with US practitioners experienced in neonatal serious illness.
  • Participants ranked the importance of 15 components for defining neonatal serious illness.
  • A working definition was iteratively refined based on expert rankings and free-text feedback.

Main Results:

  • Eighty experts participated in the initial survey.
  • Key components identified included high short-term mortality risk and shortened lifespan.
  • The final consensus definition includes high mortality risk or lifelong complexity, prognostic uncertainty, and significant impact on patient/family life.

Conclusions:

  • The developed definition of neonatal serious illness provides a standardized framework for research.
  • This definition is expected to facilitate future studies aimed at improving care for critically ill neonates and their families.