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Related Concept Videos

Infertility in Females01:28

Infertility in Females

414
Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
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Infertility in Males01:23

Infertility in Males

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Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
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Treatment Resistant Cancers02:56

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Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
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Cancer Prevention02:59

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Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
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Related Experiment Video

Updated: Sep 25, 2025

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
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Fertility Preservation in Female Patients with Cancer.

S Mahmood1, A Drakeley1, R Homburg2

  • 1Liverpool Women's NHS Foundation Trust, Liverpool, UK.

Clinical Oncology (Royal College of Radiologists (Great Britain))
|May 1, 2022
PubMed
Summary

Cancer survivors increasingly need fertility preservation due to improved survival rates and delayed childbearing. Advances in oocyte and ovarian tissue cryopreservation offer more options, but streamlined services are crucial for these complex patients.

Keywords:
COVIDCancer survivorfertilityfertility preservationsurvivorship

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Area of Science:

  • Reproductive Medicine
  • Oncology
  • Cancer Survivorship

Background:

  • Cancer treatments can impair fertility, causing significant concern for patients, especially women and transgender men, who delay childbearing.
  • Increased cancer survival rates and delayed childbearing necessitate optimized fertility preservation services.
  • Existing fertility preservation options have expanded significantly with advancements in oocyte and ovarian tissue cryopreservation.

Purpose of the Study:

  • To review fertility preservation options for cisgender women undergoing cancer treatment.
  • To highlight the need for streamlined, specialized care pathways for cancer patients requiring fertility preservation.
  • To discuss challenges in providing state-of-the-art fertility preservation services, particularly in the context of financial uncertainty and the COVID-19 pandemic.

Main Methods:

  • Literature review on fertility preservation techniques.
  • Analysis of current service provision and care pathways.
  • Discussion of challenges in managing complex patient needs.

Main Results:

  • Fertility preservation is a growing area of reproductive medicine with improved cryopreservation techniques.
  • There is a recognized need for specialist management and standardized care pathways.
  • Service provision varies regionally, and financial unpredictability poses challenges.

Conclusions:

  • All individuals with female reproductive organs should be offered fertility preservation discussions before gonadotoxic cancer treatment.
  • Specialized management and recognized care pathways are essential for complex cancer patients needing fertility preservation.
  • Improving access to and consistency of fertility preservation services is critical for cancer survivors.