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Updated: Sep 25, 2025
Building An Open-source Robotic Stereotaxic Instrument
Published on: October 29, 2013
Design and implementation of a low cost, modular, adaptable and open-source XYZ positioning system for
Thomas Campbell1, James F X Jones1
1School of Medicine, University College Dublin, Ireland.
Abstract:
In recent years, open-source 3D printing technologies have become increasingly applied to biological research. We have created a fully open-source, versatile and low cost XYZ positioning system using 3D printer components. As this system is controlled by a Python3 based operating system running on a Raspberry Pi 3 Model B, its behaviour can be adapted to meet multiple needs in neurophysiology. We have developed two main applications of this system. First, we have created an automated microscopy script that links seamlessly with image stitching plugins in ImageJ (Fiji) allowing the user to create high resolution montages. Second, we have created a series of movement scripts allowing the application of graded rates of stretch to muscle spindles. Here we outline the construction and implementation of this system and discuss how we have utilised this tool in our research.
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